BIOL 112 Lecture 10: Lecture 10 - Citric Acid.pdf

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BIOL 112 Full Course Notes
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BIOL 112 Full Course Notes
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Lecture 11 - energy pathways: citric acid/ etc! Citric acid cycle completely oxidizes the 2-c acetyl group to 2 co2 with dehydrogenases ! 4 co2 (2 per acetyl coa that enters) ! 6 nadh (3 per acetyl coa that enters) ! 2 fadh2 (1 per acetyl coa that enters) ! 2 gtp (=atp) by substrate level phosphorylation (1 per acetyl coa that enters) ! !- dehydrogenase: an enzyme that oxidizes a substrate and transfers the lost electron (hydrogen) from the substrate to an acceptor, in this case fad or nad+! 4 dehydrogenases in the citric acid cycle ! Oxidations are coupled to reduction of nad+ to made reduced election carriers (nadh. Succinate -> fumarate ! redox reactions ! Redox reaction (succinate -> fumarate) does not yield as much energy as the other. !- regulated by 1st dehydrogenase - inhibited by high nadh and h+ concentrations activated.

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