BIOL 202 Lecture Notes - Lecture 7: Aleurone, Chromosomal Deletion Syndrome, Wild Type

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Lecture 7 - transposons & gene expression i. 1940 mcclintock studied unstable alleles in maize (plant that makes corn) Wild corn are purple due to the colored aleurone gene (c) - c/c or c/c. Mutant corn are colourless (yellow) bc they are homozygous for recessive allele of colored aleurone. Cross c/c x c/c parents > variegation (both wild purple and mutant yellow seeds) Usually we would expect 50% of progenies as full purple & 50% as full colourless. Won the nobel prize for figuring out a strain of corn with a strange phenotype. Found 3 possible hybrids: purple, purple with yellow areas (variegated) Both of the following genetic factors must be present for the breakage event: Dissociation (ds) locus @ chr 9 breakpoint. Activator (ac) locus, which is unlinked to ds and c (unable to map it - different places indifferent strains) This breakage event does not ensure you have a yellow cell, you have a chance of having it.

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