CHEM 183 Lecture Notes - Lecture 2: Propofol, Levothyroxine, Millennium Pharmaceuticals
5 Oct 2018
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Foxglove- william withering 1875 account of foxglove and its medical uses . Recent concern- digoxin/lanoxin problematic for subset of heart issues (a-fib) = not perfect. Plague of athens (430-427 bc) like ebola was a great medical mystery (strong fever and foul breath) Sir william osler- mcgill faculty of medicine (1874) - medicine heart and head art not trade, listen to patient tell you the diagnosis. Humans take medicine - vs animals (but chimps/orangutans eat leaves as topical analgesic from leaf lather) Malaria- parasite -about 50% of effected victims are children mostly in africa changes brain -> lethargy/painful, -slow economic growth of africa >1% per year 120 million cases/year. Early cure was quinine (6% bark are alkaloids (rich source of quinine) 70% from bark, 600- 1200mg/ >1g per day to relieve malaria or as a preventative measure nets to prevent bug bites or remedy from artemisia annua then.
