Class Notes (834,026)
Canada (508,290)
Chemistry (1,145)
CHEM 183 (143)

Pain and Anesthetics

3 Pages
Unlock Document

CHEM 183
David Harpp

November 15 Pain and Anesthetics 1. Remarks about pain 2. Relief of pain – anesthetics 3. Pain research  Some people do not experience pain – it’s called congenital analgesia. They often can feel touch but not always temperature.  Francis Thompson 1859 – 1907 drug addict wrote a remark about pain  Emily Dickinson wrote about pain  1/5 persons suffer from chronic pain  ¼ persons over age of 65 suffer from chronic pain  No device to measure pain. It is what the person says it is.  Acute pain: results from disease, inflammation or injury – confined by time  Chronic pain: persists – representing the disease itself.  The more the pain, the longer it takes to recover  “think of pain as a disease”  The spinal cord “rewires” itself when there is pain. Pain can become permanent.  10 point pain scale in hospitals  Lebenswecker redirects the pain. o Needles at the end  Classic drug for pain: morphine – Morpheus (God and dreams) o Not addictive if given for pain (usually) o From poppy, contains opium, a narcotic  Thomas DeQuincey: Confessions of an Opium Eater (1822)  “surgical” methods prevailed for pain relief where morphine was unavailable. o Trepanation  Orthopedic surgeons were far many years all male. Now 5-10% are female. (before it required a lot of strength: the saw)  Anesthetics were needed  First anesthetic: ether o Raymundus Lullius from Spain 1275 produced sweet vitriol. H SO 2 4 o Vallerius Cordus from Germany 1540s also produced sweet vitriol o Claims!  Paracelsus born 1493. Kept records associated with ether. Wrote in a special code  CH -3H -O2H: ethanol. Heated in the presence of an acid, water is lost, ether is formed.  Ether: CH 3H -O2CH CH 2 3  Joseph Priestley 1772 created N 2 o Ammonium nitrate (a fertilizer, an explosive, a crystalline solid) is heated to create N2O and water. November 15 o “laughing gas” o Gave a high and then pass out o Propellant for whipped cream  Dr. Crawford Williamson Long 1842 credited for ether. 2 tumours removed.  Late 1800s nitrous oxide routinely used for dentists  William T. G. Morton 1846 used ether. He called it Letheon. Lethe was a river in Hell. If drunk, one would forget all and spend eternity remembering nothing of life.  Ether was bottled. Quite volatile.  John Collins Warren 1846 contacted by Morton; Massachusetts General Hospital. o Ether Dome  Two main operations of this era: 1. Amputation
More Less

Related notes for CHEM 183

Log In


Join OneClass

Access over 10 million pages of study
documents for 1.3 million courses.

Sign up

Join to view


By registering, I agree to the Terms and Privacy Policies
Already have an account?
Just a few more details

So we can recommend you notes for your school.

Reset Password

Please enter below the email address you registered with and we will send you a link to reset your password.

Add your courses

Get notes from the top students in your class.