PATH 300 Lecture 6: L6_PATH-300
Document Summary
Have selective affinity for tracheobronchial epithelial cells and destroys these cells. Symptoms are respiratory and systemic this distinguishes influenza from a cold. Symptoms include headache, fever, and myalgia (muscle pain) in addition to the classic sore throat and runny nose. Incidence has been higher than usual in north. There is a misconception that the influenza vaccine this year was less effective than usual, but this was not the case. The body"s response to deal with viral infections is both humoral and cell mediated. B cells and t cells make antibodies, and directly recognize infected epithelial cells and destroy them. Pandemic: virus has spread through the entire area known at that point in time (i. e. , global). Epidemic: virus has spread through one region. From 1500-onwards, there were 31 documented pandemics to have occurred. In 1918, one differed from all the rest. In 1918, the influenza/ spanish flu pandemic was the most deadly pandemic ever recorded in human history.