PHGY 209 Lecture Notes - Lecture 24: Streptococcus, Neutrophil, Antibody

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Innate (natural, non-specific) immunity: comes early in evolution and acts quickly, cellular and humoral factors but no memory. Most important is antibodies: also hormones, key part is about no memory. Innate response does the same thing over and over again if oyu keep stepping on glass everyday. Innate immune response: early in evolutions, danger signals, cellular factors, phagocytic cells. Interdigitating dendritic cells: cells with inflammatory mediators. Eosinophils: humoral factors, facots dissolved in the liquid of the body, acute phase reactants. Interferon-alpha: myeloid cells white cells of the body, these are the polymorphs including the neutrophil, the monocytes, macrophage and the dendritic cell, entire lymphoid system. Normal blood cell types: interested in the, neutrophils. Multiple pieces to the nucleus, surround by rbc: 5million rbc to 10"000 white cells. Second pic is neutrophil eating the streptococcus: monocytes. Macrophage: second pic is macrophage toll-like receptor reaching out to pamp on bacteria, forms a false lymph a pseudopod.

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