BIOCHEM 2EE3 Lecture 7: Module 4 Video 1

30 views15 pages

purplehound890

8 Dec 2017

School

Department

Course

Professor

For unlimited access to Class Notes, a Class+ subscription is required.

Document Summary

They are the implementers of many required cellular processes in the cell. The function of each protein is dictated by their structure and the structure of each protein is dictated by their primary sequence: the seque(cid:374)(cid:272)e of a(cid:373)i(cid:374)o a(cid:272)ids. He(cid:396)e i"(cid:448)e displa(cid:455)ed a f(cid:396)ag(cid:373)e(cid:374)t of the p(cid:396)i(cid:373)a(cid:396)(cid:455) st(cid:396)u(cid:272)tu(cid:396)e of the protein myoglobin. This primary structure contains a very unique blueprint of amino acids, which contain diverse side chains. These side chains have unique chemical properties which are involved in driving the folding of the protein into the 3-d structure we see here. So let"s sta(cid:396)t at the (cid:271)egi(cid:374)(cid:374)i(cid:374)g: the p(cid:396)i(cid:373)a(cid:396)(cid:455) st(cid:396)u(cid:272)tu(cid:396)e, (cid:449)hi(cid:272)h is just the se(cid:395)ue(cid:374)(cid:272)e of the a(cid:373)i(cid:374)o a(cid:272)ids i(cid:374) a polypeptide chain. The secondary structure starts to get into the folding bit and is driven primarily by the peptide backbone interactions. Remember that the peptide bond formed between 2 amino acids looks like this.

Related Questions

1. Which of the following is the correct sequence of events (from start to finish) in cellular fatty acid oxidation?

A. Fatty acid activationÃ carnitine shuttleÃ beta-oxidation

B. Beta-oxidationÃ carnitine shuttleÃ Fatty acid activation

C. Fatty acid activationÃ carnitine shuttleÃ beta-oxidation

D. Carnitine shuttleÃ Fatty acid activationÃ beta-oxidation

2. What reaction is catalyzed by lipoprotein lipase, or lipase?

A. Hydrolysis of TAGs into fatty acids and glycerol

B. Hydrolysis of TAGs into amino acids and glycerol

C. Hydrolysis of cholesterol in to fatty acid and water

D. Hydrolysis of cholesterol into acetyl-CoA

3. How do fatty acids of different carbon lengths cross into the mitochondrial matrix for oxidation?

A. Small FAs of 10 carbons or fewer can freely diffuse through the membrane

B. Large FAs are cleaved into two smaller units that are actively transported across the membrane

C. A membrane-bound transferase catalyzes the conversion of long-chain FAs and FA-carnitine esters, which are transported across the membrane via a specific carrier

D. The breakdown of large FAs starts outside the matrix, allowing for the smaller particles to pass easily through the membrane

4. How can any RNA nucleotide be easily distinguished from a DNA nucleotide?

A. RNA nucleotides have a unique phosphodiester bond linkage

B. RNA nucleotides have uracil nitrogenous bases

C. RNA nucleotides have an -OH on the 2â carbon of the ribose

D. RNA nucleotides cannot be easily distinguished from DNA nucleotides

5. Which of the following statement is true concerning the sequence pTACGTAACGTA?

A. This is an RNA sequence

B. In order to have a more rigid structure in a double-stranded molecule, the sequence given would need more adenosine

C. If the complementary strand were present, the number of purines would be equal to the number of pyrimidines

D. The amount of purines is equal to the amount to pyrimidines

6. Complementary base pairing is considered which level of structure?

A. Secondary

B. Tertiary

C. Quaternary

D. Primary

7. Which of the following is/are required for the polymerization reaction catalyzed by DNA polymerase III?

I. RNA primer

II. DNA primer

III. RNA template

IV. DNA template

V. NTPs

VI. dNTPs

VII. Magnesium

VIII. Calcium

A. II, IV, V, and VII

B. II, IV, VI, and VII

C. I, IV, V, and VIII

D. I, IV, VI, and VII

8. DNA polymerase I, from E. coli, has three different catalytic sites. Which of the following is NOT one of them?

A. RNA-dependent RNA polymerase

B. RNA-dependent DNA polymerase

C. DNA-dependent RNA polymerase

D. DNA-dependent DNA polymerase

9. Eukaryotes solve the problem of replicating the ends of their linear chromosomes by:

A. Using a protein as primer

B. Enzyme activity that uses an RNA template and reverse transcription in a series of repeat cycles

C. All of the listed solution

D. Terminal redundancy whereby each end of the chromosome is duplicated allowing recombination

Question 1

Not yet answered

Marked out of 1.00

Flag question

Question text

The function of tRNA is to

Select one:

a. provide a site for polypeptide synthesis

b. transport amino acids to the ribosome

c. transcribe DNA

d. transform DNA

Question 2

Not yet answered

Marked out of 1.00

Flag question

Question text

The lipid bi-layer is

Select one:

a. hydrophilic

b. hydrophobic

c. hydrophilic and hydrophobic

d. depends on the surrounding medium

Question 3

Not yet answered

Marked out of 1.00

Flag question

Question text

Which of the following statements is FALSE?

Select one:

a. carbohydrates are generally hydrophilic molecules.

b. living things use carbohydrates for structure and for energy storage.

c. carbohydrates are composed principally of carbon, hydrogen, and oxygen.

d. none of the above â they are all true

Question 4

Not yet answered

Marked out of 1.00

Flag question

Question text

Which of the following terms correctly describes a compound featuring more than one double bond?

Select one:

a. saturated

b. polyunsaturated

c. monounsaturated

d. disaturated

Question 5

Not yet answered

Marked out of 1.00

Flag question

Question text

Eukaryotic mRNA transcripts are protected from modification by

Select one:

a. 5' caps

b. 5' poly-A caps

c. 3' caps

d. 5'-3' poly tails

Question 6

Not yet answered

Marked out of 1.00

Flag question

Question text

The methods of membrane transport that don't require protein channels or carriers are

Select one:

a. osmosis

b. diffusion

c. phagocytosis

d. exocytosis

e. all of the above

Question 7

Not yet answered

Marked out of 1.00

Flag question

Question text

Complete the following sentences: "Primary active transport is dependent on __________. Secondary active transport is dependent on __________ created by __________.

Select one:

a. channel proteins, electrochemical gradient, carrier proteins

b. electrochemical gradient, ATP, mitochondria

c. electrochemical gradient, ATP, primary active transport

d. ATP, electrochemical gradient, primary active transport

e. carrier proteins, electrochemical gradient, channel protein

Question 8

Not yet answered

Marked out of 1.00

Flag question

Question text

Which of the following is a reduced compound?

Select one:

a. CO2

b. O2

c. N2

d. NAD +

e. NADH

Question 9

Not yet answered

Marked out of 1.00

Flag question

Question text

Gel electrophoresis separates DNA fragments according to their:

Select one:

a. base sequence

b. size

c. percentage of labelled nucleotides

d. electrical charge

Question 10

Not yet answered

Marked out of 1.00

Flag question

Question text

G0 is:

Select one:

a. part of interphase

b. the phase of the cell cycle where DNA replication occurs

c. the phase of the cell cycle where two identical daughter cells are created

d. a special "resting" phase in which cells are in a non cycling state

e. a special phase where the number of chromosomes in a parent cell is reduced by half such that each daughter cell contains only one member of a pair of homologous chromosomes

Question 11

Not yet answered

Marked out of 1.00

Flag question

Question text

At which pH will the concentration of hydrogen ions be equal to the concentration of hydroxide ions?

Select one:

a. pH 1

b. pH 5

c. pH 7

d. pH 9

e. pH 14

Question 12

Not yet answered

Marked out of 1.00

Flag question

Question text

Which of the following enzymes has proofreading activity?

Select one:

a. Ligase

b. Helicase

c. Topoisomerase

d. DNA polymerase

e. Peptidyl transferase

Question 13

Not yet answered

Marked out of 1.00

Flag question

Question text

The process of _______________ cuts introns from the primary transcript and the final "processed" mRNA is produced.

Select one:

a. RNA cleaving

b. RNA translocation

c. RNA elongation

d. RNA splicing

Question 14

Not yet answered

Marked out of 1.00

Flag question

Question text

Transcription is initiated when RNA polymerase binds to

Select one:

a. a promoter

b. an initiator

c. a transciptor

d. a codon

Question 15

Not yet answered

Marked out of 1.00

Flag question

Question text

Complete the following sentences: "__________ connect the extracellular matrix with microfilaments. __________ connect intermediate filaments from adjacent cells."

Select one:

a. Cadherins, Integrins

b. Connexins, Cadherins

c. Integrins, Cadherins

d. Integrins, Connexins

e. Connexins, Integrins

Question 16

Not yet answered

Marked out of 1.00

Flag question

Question text

Which of the following regions of RNAs are translated?

Select one:

a. 5' UTR

b. exons

c. introns

d. 3' UTR

e. poly-A

Question 17

Not yet answered

Marked out of 1.00

Flag question

Question text

Control of gene expression in eukaryotic cells occurs at which level(s)?

Select one:

a. only the transcriptional level

b. epigenetic and transcriptional levels

c. epigenetic, transcriptional, and translational levels

d. epigenetic, transcriptional, posttranscriptional, translational, and posttranslational levels

Question 18

Not yet answered

Marked out of 1.00

Flag question

Question text

Cellular organelles containing hydrolytic enzymes are called:

Select one:

a. peroxisomes

b. lysosomes

c. ribosomes

d. mesosomes

Question 19

Not yet answered

Marked out of 1.00

Flag question

Question text

______ are chemicals or combinations of chemicals that take up excess hydrogen ions or hydroxide ions in order to keep the pH constant.

Select one:

a. acids

b. bases

c. salts

d. buffers

e. carbohydrates

Question 20

Not yet answered

Marked out of 1.00

Flag question

Question text

Which of the following proteins appear in some stages of the cell cycle and are degraded at other stages?

Select one:

a. kinases

b. cyclins

c. nucleotides

d. phosphatases

e. none of the above

Question 21

Not yet answered

Marked out of 1.00

Flag question

Question text

Which of the following correctly matches an organelle with its function?

Select one:

a. mitochondrion photosynthesis

b. nucleus cellular respiration

c. ribosome manufacture of lipids

d. lysosome movement

e. central vacuole storage

Question 22

Not yet answered

Marked out of 1.00

Flag question

Question text

What is the sequence corresponding to the following electropherogram obtained by Sanger sequencing (green: A; red:T; black: G; blue: C)?

Select one:

a. CCGTTATGAAC

b. GGCTTATGAAG

c. CAACTATTGCC

d. GGCAATAGTTG

e. CCGTTATCAAC

Question 23

Not yet answered

Marked out of 1.00

Flag question

Question text

Which of the following statement is true

Select one:

a. the two DNA strands are parallel and complementary

b. the two DNA strands are anti parallel and non-complementary

c. the two DNA strands are anti-parallel and complementary

d. none of these

Question 24

Not yet answered

Marked out of 1.00

Flag question

Question text

The energy-requiring process by which small molecules are joined to form larger molecules is specifically called

Select one:

a. metabolism

b. anabolism

c. catabolism

d. enzymatic reactions

Question 25

Not yet answered

Marked out of 1.00

Flag question

Question text

When DNA replication starts

Select one:

a. the phosphodiester bonds between the adjacent nucleotides break

b. the bonds between the nitrogen base and deoxyribose sugar break

c. the leading strand produces Okazaki fragments

d. the hydrogen bonds between the nucleotides of two strand break

Question 26

Not yet answered

Marked out of 1.00

Flag question

Question text

A(n)_______ is the movement of a segment of a chromosome from one chromosome to another nonhomologous chromosome

Select one:

a. inversion

b. translocation

c. deletion

d. duplication

Question 27

Not yet answered

Marked out of 1.00

Flag question

Question text

Complete the following sentences: "Replication forks from the same origin of replication extend __________. __________ DNA strand is used as template for the leading strand at one fork and for the lagging strand at the second fork. New DNA is synthesized from 5' to 3' on the __________."

Select one:

a. unidirectionally, A different, both the leading and lagging strands

b. bidirectionally, The same, leading strand

c. bidirectionally, The same, lagging strand

d. unidirectionally, A different, leading strand

e. bidirectionally, The same, both the leading and lagging strands

Question 28

Not yet answered

Marked out of 1.00

Flag question

Question text

Manufacturing recombinant DNA molecules involves cutting a gene from its normal location, inserting it into a circular piece of DNA from a bacterial cell, and then transferring the circle of DNA to cells of another species. Which of the below describe the circular piece of DNA?

Select one:

a. restriction enzyme

b. plasmid

c. bacteriophage

d. transposon

Question 29

Not yet answered

Marked out of 1.00

Flag question

Question text

Complete the following chemical equation to make it balanced: glycerol + ___ ? triacylglycerol + ___

Select one:

a. 3 fatty acid, 3 H2O

b. fatty acid, H2O

c. 3 OH-, 3 H+

d. 3 H2O, 3 fatty acid

e. fatty acid, 3 H2O

Question 30

Not yet answered

Marked out of 1.00

Flag question

Question text

Which structure is found in plant cells but not animal cells? Check all that apply.

Select one or more:

a. Cell wall

b. Chloroplast

c. Plastid

d. Central vacuole

e. Lysosomes

brownhound170

BIOCHEM 2EE3 Lecture 7: Module 4 Video 1

Document Summary

Get access

Related Documents

BIOCHEM 2EE3 Lecture Notes - Lecture 3: Alpha Helix, Beta Sheet, Carboxylic Acid

BIOCHEM 2EE3 Lecture Notes - Lecture 4: Amide, Protein Folding, Steric Effects

BIOCHEM 2EE3 Lecture Notes - Lecture 7: Procollagen-Proline Dioxygenase, Scleroprotein, X-Ray Crystallography

Related Questions