BIOLOGY 1A03 Lecture 20: Lecture 20

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BIOLOGY 1A03 Full Course Notes
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BIOLOGY 1A03 Full Course Notes
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Non-disfunction: the improper separation of chromosomes and the result is the offspring may have an abnormal amount of chromosomes in its cell. Friday, march 20, 2015: brief period of mitosis, entry into mitotic arrest (pre-birth, after birth, male (add info) Occasionally, nondisjunction occurs: members of a pair of homologous chromosomes do not move apart properly in meiosis i, or sister chromatids fail to separate during meiosis ii. Results: one gamete receives 2 of the same type of chromosome and another receives no copy (other chromosomes are usually distributed normally) Nondisjunction also occurs in mitosis but doesn"t impact entire organisms: may just result in tumour. !2: for any giving amount of births there are a number of diseases that can be caused by an extra chromosome or a lack of chromosome (nondisjunction) ex. Down syndrome (47, +21) 13/10,000 live births ex. Turner syndrome (45, x) only known viable disease where a chromosome is missing.

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