HTHSCI 1DT3 Lecture Notes - Lecture 12: Immunoglobulin G, Proinflammatory Cytokine, Protein Kinase A
13 Aug 2020
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Document Summary
Mod. 3-11 the basis of neonatal immunology 1. Mod. 3-11 the basis of neonatal immunology: understand current hypotheses regarding the association of neonatal experiences with long term respiratory health, understand the importance of respiratory infections in early life, understand the mechanisms underlying failure of vaccination in neonates. The influence of early life on respiratory health by: respiratory infections, 26% of neonatal deaths are caused by pneumonia as they are particularly susceptible to infectious disease, respiratory pathogens (bacteria and viral) include: respiratory syncytial virus (rsv), Bortetella pertussis (whooping cough), streptococcus pneumoniae and haemophilus influenzae b (hib) (unrelated to influenza virus: pre-school children get 6-10 respiratory infections per year (75% viral and 25% bacteria) and most lead to common colds (upper respiratory tract infection) But cost on cold remedies chalk up to billion per year in us: clinical importance of rsv. Almost all children get rsv by 2 years old, with the highest risk group being from 1 .
