MEDRADSC 2S03 Lecture Notes - Lecture 5: Oral Mucosa, Salivary Gland, Lymph Node
Document Summary
Lips, ant 2/3 of tongue, gingiva (gums), buccal mucosa (lining of lips and cheeks), floor of mouth, hard palate (bony top of mouth), retromolar trigone (area of the gum behind the wistom teeth) Nasopharyx (behind nose), oropharynx (soft palate, back of mouth, base of tongue, tonsils), hypopharynx (distal end - stops at esophague) Varies by site: 3-5% of all cancers, men > women, >50 years old, race: whites slightly higher (depending on cancer, npc: bimodal peak. Increased incidence in young adults, then another peak ~50-70 years of age. Causes majority of all head and neck cancers. Especially cancer of the oral cavity, oropharynx, hypopharynx and larynx (respiratory mucosa) Not risk factors for salivary gland cancers or npc. Betel nut chewing or paan (betal liquid) (asia & africa) Mate - tea-like drink from south america. A and t are not necessarily factors. Hpv - 16 (oropharyngeal ca - tonsils, base of tongue)