MEDRADSC 2T03 Lecture Notes - Lecture 2: Hematopoietic Stem Cell Transplantation, Total Body Irradiation, Umbilical Cord
27 Jun 2016
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Procedure to replace damaged or destroyed bone marrow with healthy bone marrow stem cells1. Stem cells are immature cells found in the bone marrow that give rise to all the different blood cells (rbc, wbc, platelets)1. Umbilical cord: stem cells removed from newborn baby"s umbilical cord right after birth; stem cells frozen and stored until needed for a transplant; type of allogeneic bone marrow transplant o. Syngeneic: stem cells removed from an identical twin. Before transplant1: chemotherapy or total body irradiation. Collecting bone marrow1: bone marrow aspirated from hip; patient normally asleep for procedure, marrow put in a freezer until ready. Risks1: chest pain, drop in blood pressure o o. Funny taste in mouth: headache, hives, nausea (stomatal given to prevent vomiting, pain o. References: bone marrow transplant: medlineplus medical encyclopedia. (n. d. ). 2016, from https://www. nlm. nih. gov/medlineplus/ency/article/003009. htm: stem cell transplant for acute myeloid leukemia. (n. d. ).
