HLTH 101 Lecture : a) N

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A healthy immune usually is effective in combating disease. It includes: 1) physical barriers (ie. skin, mucous membranes: active removal (ie. urinary flushing, mucsal escalator system: cilia in upper respiratory tract, destruction (ie. lysozymes in tears, acids in gi tract, phagocytosis, monocytes, neutrophils, and macrophages) Fever: temperature rises 2 degrees when fighting infection. Lactoferrin (prevents iron binding: microbes need iron to survive: specific. Relies on antigens (can be specific (ie. 1 amino acid in a protein) or a molecule (ie. molecular fingerprints)) 3 traits: 1) diverse (responds to different antigens) 3) memory (remembers antigen, provides rapid response for subsequent infection) Signal helper t lymphocytes to recognize antigens (see diagrams) B-cells proliferate into two reponses: primary response. Helper t-cells stimulate cytotoxic t-cells via cytokines (see diagram) Cytotoxic t-cells release substance that penetrate the cell membrane of the microbe. Due to possibly too long of response to virus: immunization. Memory may not last for life (ie. booster shot)

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