MICR 221 Lecture Notes - Lecture 6: Dextran, Desiccation, Biofilm
24 Apr 2018
School
Department
Course
Professor
Document Summary
S isolation b=gram +ve, a= gram ve, c=archaea. Only seen w electron microscopy, covers entire surface of cell. In lad, it becomes lost bc mutant w/o s layer has a growth advantage, Attachment of subunits of layer and to outer memb wall has non covalent bonds. Resistant to viruses, predatory bacteria, enzymes, antibodies, complement (series of proteins that lyse) via pores. Acidic, deficient in s containing aa 40-200 kda in size center to center spacing 3-35 nm, has no defined pore size used as a giant filter for cell. 500,000 copies to cover cell synthesize, translocate and incorp up to. 500 copies/sec represents up to 10% of total cell protein synthesis from a single gene have a very strong promoter so used in expression vectors in biotech. Much more uniform size than polymer based sys. Widespread in nature, lost in lab due to mutant arising expensive. Numerous fibers of polysaccharide extending up to 50 um from surface, acidic.
