PHAR 100 Lecture Notes - Lecture 15: Blood Alcohol Content, Ethanol Metabolism, Gaba Receptor
4 May 2016
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Document Summary
State the properties of ethanol in terms of absorption, distribution, and biotransformation. Describe the effect of various blood alcohol concentrations on central nervous system function. Explain the proposed mechanism of neuronal inhibition of ethanol. Discuss the effects of ethanol on the central nervous system, cardiovascular system, gastrointestinal tract, and liver in terms of short-term and chronic use. List the effects of ethanol on the developing fetus. The first use as a fermented beverage was 8000 b. c. from honey, and is still used recreationally. 10-13 ml of absolute alcohol is the amount metabolized by the liver each hour. The stomach emptying time (time required to reach the small intestine) Ethanol concentration in the gi tract and the presence of food. The time from the last drink to the maximal blood alcohol concentration ranges from 30-90 mins. Goes through the total body water and goes across the blood brain barrier.
