PHAR 100 Lecture Notes - Lecture 10: Angiotensin, Sympathetic Nervous System, Aldosterone

• School: Queen's University
• Department: Pharmacology and Toxicology
• Course: PHAR 100
• Professor: Courtney Green

Document Summary

Bp (blood pressure) the force that the circulating blood exerts on the walls of the arteries: normal: 120/80 (120: range between 90-140) o o. Factors controlling bp: high volume, high pressure and vice versa. Peripheral resistance (pr: vasoconstriction (vs) high pr, high bp, vasodilatation (vd) low pr, low, bp, activity of sympathetic nervous system (sns) activity: Enzyme called renin secreted by the kidney that lowers blood pressure. It converts angiotensin i converted into angiotensin ii causing vc: adh (anti-dieuretic hormone) and aldosterone cause salt and water retention and bring blood pressure back up, allows blood pressure to rise or fall. Risk factors: uncontrollable: men more likely than women because of female sex hormones, family history o. Life long, aim at lowering the incidence of complications. Treatment: non pharmacological: adjust lifestyle through body weight, avoid salt and high lipid food. Get adequate amounts of potassium, calcium, and magnesium. No smoking or drinking, walking, avoid major stress if possible.