FNN 100 Lecture Notes - Lecture 14: Lycopene, Zeaxanthin, Phytoestrogens

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The only form recognized to meet human needs. Found in the blood in highest concentrations. Believed to be most biologically active form r/t as bound to alpha-tocopherol transfer protein in the liver which helps distribute it. Vitamin e is an antioxidant: si(cid:374)(cid:272)e pufas a(cid:396)e pa(cid:396)ti(cid:272)ula(cid:396)ly susceptible to oxidative damage. Need increased vit e as pufa intake increases: helps p(cid:396)ote(cid:272)t ldl-c from oxidation may also protect against other steps in atherosclerosis e. g. formation of blood clots, p(cid:396)ote(cid:272)tio(cid:374) of (cid:272)ell (cid:373)e(cid:373)(cid:271)(cid:396)a(cid:374)es, pa(cid:396)ti(cid:272)ula(cid:396)l(cid:455) (cid:449)here [o2] are high. Vitamin e deficiency: a(cid:396)e (cid:449)ith (cid:449)ide-use of oils & fact that we store it. U(cid:374)less fat a(cid:271)so(cid:396)ptio(cid:374) o(cid:396) vit e (cid:373)eta(cid:271)olis(cid:373: si(cid:374)(cid:272)e (cid:396)ole i(cid:374) p(cid:396)ote(cid:272)tio(cid:374) of (cid:272)ell (cid:373)e(cid:373)(cid:271)(cid:396)a(cid:374)es, deficiency can cause membrane changes, s(cid:455)(cid:373)pto(cid:373)s a(cid:396)e usuall(cid:455) (cid:374)eu(cid:396)ologi(cid:272)al. Supplements & toxicity: e(cid:448)e(cid:374) though defi(cid:272)ie(cid:374)(cid:272)(cid:455) is (cid:396)a(cid:396)e, still ++supple(cid:373)e(cid:374)ts (cid:449)ith ++(cid:272)lai(cid:373)s. Hair, fertility, immunity, athletic performance etc no conclusive evidence to support: mu(cid:272)h (cid:396)esea(cid:396)(cid:272)h i(cid:374)to vit e a(cid:374)d hea(cid:396)t disease & (cid:272)a(cid:374)(cid:272)e(cid:396)

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