Kins 140 Lecture 5 Prof Arnold

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kins 140
lecture 5 Infectious Disease 2
September 22
The Immune System:
-combating infectous disease
-development of diseases
Innate Immunity:
-defenses our body has to address pathogen (not to specific pathogen)
Acquired Immunity:
-ability to recognize specific foreign substances
The body’s defenses against infectious diseases
external:
-mechanical barriers
-skin, depends on being unbroken, healthy nutrition maintains turnover
-mucous membranes, nasal and pubic hairs, cilia, eyelashes
-blinking, sneezing, coughing, vomiting.
chemical defenses:
-secretions: sebum of skin, saliva, tears, acid in gut, genital
-enzymes, acid
Internal
-general systemic responses:
-inflammatory response
-histamine release from mast cell swelling (to contain
infection or injury)
-cytokines: provides msges to immune system to kick in.
-Fever -cytokine pyrogens
-can be harmful, but paradoxically it can be protctive
-increased body temp (by one or two degrees) kills many agents
and increases white blood cell activity
Acquired Immunity
-the process of priming the body to remember an encounter with a specific antigen
-get the body to remember how to deal with a pathogen
Active:
-body produces own way to recognize and deal with specific pathogen (memory to get
rid of it)
-builds immunity
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