MMI133 Lecture Notes - Lecture 2: Disseminated Intravascular Coagulation, Neisseria Meningitidis, Gram Staining

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How would you classify the gram stain: simple stain, differential stain (answer, capsule stain, negative stain. Classified into families on the basis of the relatedness of genetic info (use rrna) If we want to talk about all subtypes in genus staphylococcus, can say. How do we tell bacteria apart if they are the same shape: simple stains: colored bacteria on white background, differential stains does not penetrate through the cell wall; acid fast penetrates the cell wall. Most important practical distinction to know about bacteria = staining characteristic. Gram stain: separates bacteria into 2 major groups. Acid-fast: used for mycobacteria (tb); tb has a lot of waxes; crystal violet in gram stain. Still used as one of the major diagnostic tests used to id disease causing bacteria. Based on cell wall structure: amt of peptidoglycan in bacterial cell wall. As one cause of: meningitis; fastest killing variant of the genus. Define meningitis and explain what the meninges are.

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