MMI133 Lecture Notes - Lecture 14: Enterococcus, Passive Transport, Neutrophil

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Describe the differences between normal flora and transient flora. Describe different types of infections including nosocomial infections. List hazards you face as a health care professional. Animals and humans are free of microbes in utero, in healthy situation acquire bacteria at and after birth. Newborns first contact with bacteria is usually lactobacilli from mothers vagina. With breastfeeding and exposure to the environment, foods and people other types of organisms are able to colonize their skin and intestinal tracts. Microorganisms that may be present on body surfaces temporarily (days, weeks or months), then disappear. Can be either pathogenic (disease causing) or nonpathogenic. Do not necessarily cause disease unless special conditions prevail. Human body may contain 10 x more bacterial cells than human cells (1 x 1013 human cells) (1 x 1014 bacterial cells) Normal flora prevent the overgrowth of harmful microorganisms. Involves competition for nutrients, cellular receptors, production of substances that affect ph and available oxygen.

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