MMI133 Lecture Notes - Lecture 14: West Nile Fever, Candida Albicans, Human Microbiota
2 Feb 2017
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Mainly alpha hemolytic), gi (bacteroides fragillis), vagina (lactobacilli) and skin (staph epidermidis) How infections get started: pathogens find suitable host, pathogen adhere to host cells and tissues, pathogen penetrates host defenses, but sometimes, can produce disease without penetrating the body defenses by releasing toxins. What normal flora do for us: microbial antagonism. Normal flora prevent the overgrowth of harmful microorganism. Involves competition for nutrients, cellular receptors, production of substances that affect ph and available o2. If balance is upset, disease can result: ie: candida albicans cannot grow in ph of 3. 5-4. 5 in normal flora in fertile adult women that have lactobacilli which metabolize glycogen and lower ph** Yeast infection and grow by douching: **e. coli in large intestine: Produce bacteriocins (proteins that inhibit the growth of other bacteria of the same closely related sp, such as pathogenic. Salmonella or shigella: **growth of clostridium difficile in the large intestine:
