MMI133 Lecture 27: Chapter 18 - Urinary Tract and Neonatal Infections
16 Jul 2018
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Document Summary
Most infections are acute, non-complicated (e. g. cystitis, urethritis) Severe infections with complications affect kidney function (pyelonephritis) Valves controls against backwards flow of urine. Low ph (especially in those that eat meat) Flushing or urine: mechanism of physical defense. Urine sedimentation test: diagnosis of complicated infection, casts (indications of urine disease, are usually protein) important. Analysis of content, osmolality, protein and glucose. Lower uti painful urination (dysuria) urgency and frequency of micturition (fancy way of saying peeing) increased catheter related infections are usually asymptomatic cloudy urine due to wbc (pyuria) and bacteria (bacteriuria) Upper uti (kidneys) fever and similar symptoms to lower uti. Pyelonephritis - infection of the kidney (most significant danger from lower uti infection) E. coli, motile + or negative capsule has o (somatic), h (flagellar), k (capsular), f (fimbrial) antigens. Adhesion: p-fimbriae attach to uroepithelial cells usually susceptible to many antibiotics.
