NU FS305 Lecture Notes - Lecture 7: Constipation, Cirrhosis, Carcinoma
3 Jan 2017
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All mitochondria dna comes from the maternal side. Linking back to the regulation of muscle protein synthesis and degradation. Chemical reactions can be coupled or synergistic reactions. Work of the liver: intestine first pass metabolism nutrients, xenobiotics, drugs. Upon entering the cell, glucose is converted to glucose-6-phosphate. Glucose-6-phosphate can be used for: glycolysis, glyconeogenesis, or converted to pentose phosphate. Glucose not just used for energy, but for other pathways too. First step in glycolysis, glyconeogenesis, and pentose phosphate pathway. Quick release of energy (glucose to pyruvate get 4 atp) Anaerobic vs aerobic pathways lactic acid pyruvate (lactate dehydrogenase) Conversion of 5-c sugars into intermediates in the glycolysis pathway. Atp produced by electron transport chain in mitochondria. How nutrients feed in also a factor in how they will be used. Acetyl coa metabolic fate regulated by atp level. Atp s(cid:455)(cid:374)thesis fa/tg fro(cid:373) a(cid:272)et(cid:455)l coa (other substrates stored: glucose, aa, glycerol) Acetyl coa not a substrate for synthesis glucose or aa.
