PHYSL210B Lecture Notes - Lecture 10: Sex Steroid, Corpus Spongiosum Penis, Gonadotropin
Document Summary
Hormones are usually lipid soluble so they can easily enter the cells. They bind their corresponding receptor inside the cell. Once it forms the hormone-receptor complex, the complex diffuses inside the nucleus. In the nucleus, it can bind dna and modify mrna formation. Modification in protein synthesis and circulating protein concentration. This is called the classical genomic pathway. In general, gonadal steroids develop accessory reproductive organs: duct system for carrying sperm or eggs, breast development (influenced by ovarian hormones), gynecomastia in males causes by diuretics and other types of drugs that reduce amount of androgens. Secondary sexual characteristics: hair distribution patter (pubic hair, body hair, body shape (wider hips, breasts in females, height, voice, muscle growth. The brain is more important in controlling reproductive physiology than the reproductive system itself. A cascade of events in the brain that allows proper functioning of gonads in males and females.