BIOM 4070 Lecture Notes - Lecture 3: Organic Compounds (Minerals), Osteoblast, Calcium Metabolism
30 Jan 2018
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Document Summary
Specialized type of ct: stiff, pliable, resilient and gel like. Resists mechanical stresses, absorbs shock, slides on surfaces. Avascular: limits size, has poor capacity for repair, low anaerobic metabolism. Function: supports soft tissue, facilitates bone movement, guides bone development. Location: articular surfaces of bones, ears and nose, airways and lungs, growth plates on bones. 95% of volume; solid and firm; but pliable. 40-80% glycosaminoglycans (gags e. g. hyaluronic acid, chondroitin sulfate), proteoglycans (e. g. aggrecan) and glycoproteins (e. g. proteoglycans (e. g. aggrecan) and glycoproteins (e. g. chondronectin) Remainder is mostly water molecularly bound to gags. Generally, collagen type 2 limits compressive deformation, resists tension. Also elastin (in elastic cartilage) and collagen type 1 (in fibrous cartilage) Form a dense ct layer called the perichondrium (not found in all types of cartilage) Reside in a cavity called a lacuna. Fetal skeleton precursor cartilage for bone. Same as hyaline: also contains elastin fibres. Dense ct regions rich in collagen type 1.
