NUTR 3210 Lecture Notes - Lecture 1: Pellagra, Osteomalacia, Paleopathology
Document Summary
Ancient pop"s: high infant and overall mortality rate shorter life spans. Infectious disease (due to decreased vit a?) 5th century bc showed earliest known records and understanding of nutrients which came form ancient. The decline of rome lead to the dark ages and eventually lead to the italian renaissance. 17th century provided quantitative approaches and empirical methods that alluded to the concept of metabolism. 16th century showed some nutrients are essential and supplementation can improve health. 19th century had scientific work purify diets leading to the notion of vitamins & importance in preventing diseases caused by deficiencies. Purified diets= protein & fat & chd alone, could not support life in experimental animals except models used to discover vitamins & minerals. Black tongue" in dogs is equivalent to pellagra in humans. Scurvy was caused by salt, pork, bread, and rum. Swelling in the gums, joints, bleeding, death (> 1 million sailors) 2 oranges and a lemon cured scurvy.