NUTR 4210 Lecture Notes - Lecture 9: Adipokine, Hyperinsulinemia, Acute-Phase Protein
22 Dec 2017
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Cancer (part 1: metabolic changes during cancer, very similar to obesity (inflammation, etc. , advanced cancer where patients are losing a significant amount of body weight, management, nutritional and lifestyle interventions. Cancer is characterized by abnormal cell growth and division: normal call growth is controlled and highly regulated. When this is lost, cells keep growing and dividing mass of tissue (tumour) Nutr*4210 immune system that is (cid:373)ea(cid:374)t to re(cid:272)og(cid:374)ize (cid:862)i(cid:374)truders(cid:863), (cid:271)ut the pro(cid:271)le(cid:373) occurs when damage occurs and these defense mechanisms are not doing their job. O it would the(cid:374) (cid:271)e (cid:272)alled, (cid:862)(cid:271)reast (cid:272)a(cid:374)(cid:272)er with (cid:271)o(cid:374)e (cid:373)etastasis(cid:863): more serious phase of cancer, because tumours are forming in multiple sites. It"s o(cid:374)l(cid:455) (cid:271)ee(cid:374) i(cid:374) the last (cid:1005)(cid:1004)-15 years that more cancers are being related to obesity. Tnf-a: sets up a great environment for tumour cells to grow. Obesity is associated with metabolic abnormalities that may increase cancer risk. Insulin resistance and hyperinsulinemia: altered hormone metabolism, promotes a fabourable environment for the tumour.
