BIOL 2410 Lecture Notes - Lecture 31: Hypercalcaemia, Colloid, Ovulation
Document Summary
Secretions of all 6 hormones produced by the anterior pituitary are controlled by neurohormones released by the hypothalamus. All but one hormone seceded form the anterior pituitary exert their effects on other endocrine glands: growth hormone (gh): Released in response to growth hormone releasing hormone (ghrh) secretion form the hypothalamus. Somatostatin (gh inhibiting hormone) inhibits gh release. Growth includes; increase in bone length, cell proliferation and cartilage and biomolecule synthesis. Increase in elongation and diameter of the body. Gh is the most abundant hormone in the anterior pituitary. Secretion is spontaneous through out the day but peaks during the rst 90 minutes of sleep. Testicular testosterone plays a role in males. Female testosterone comes from the adrenal cortex - very small supply. Adrenal androgens are more important in females. Growth always stopes because of the effects of estrogen and testosterone. Gh mediates its effects through somatomedin -> igf i and igf ii.