MBIO 2370 Lecture 6: Lecture 6 – MBIO 2370
10 Feb 2017
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Document Summary
Use lipids to make acetyl-coa: breakdown of lipids make a lot of acetyl coa, also make potential energy that can be used for etc or other reactions. Breakdown products of lipids enter the tca cycle. Bulk of energy come from fatty acids: b-oxidation into accoa. Fas are amphipathic long chain aliphatic carboxylic acids. The long chain saturation fa are the least soluble in water: after 6 wont dissolve. Not often found in cells in free form but instead are combined in complex lipids. Most are monocarboxylic acids with linear (unbranched) hydrocarbon chains: most have an even number of c carbons, shorter, longer, odd numbered, branched or cyclic fatty acids all occur, but at a much lower frequency. Unsaturated fatty acids (one or more double bonds) are also common: most common are c18 and c20 acids. If more than one double bond, they are almost always separated by a single methylene group: double bonds increases the boiling point of the fat.
