MBIO 2370 Lecture 13: MBIO 2370 – Lecture 13
17 Mar 2017
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Storage of ga-3-p and oaa occurs via gluconeogenesis: this is essentially the reversal of glycolysis, with a couple of extra enzymes added, draw, once we get glucose, we can store it as glycogen or starch. In plants - starch: polymer of glucose (amylose and amylopectin) In animals - glycogen: branch polymer like amylopectin (alpha1-4 and a1-6 linkages) but much more densely branched. Stored in the liver (as much as 7% weight) and some in muscle: easily deplete this by exercise or starvation, then you would metabolism fats and amino acids. Carbohydrate polymers: draw, have a reducing and non reducing end. Starch granules in plant cells: glycogen granules in animal cells. Gluconeogenesis: pyr-oaa-pep-2pga-3pga-1,3bispga-ga3p - frc 1,6bisp - frc6p - glc6p, excess glucose produced in this way can then be stored as glycogen, glc6p --> glc-1-p glycogen, an in plants, glucose is stored as sucrose and starch: Starch synthase: glc1p --> adp-glucose + starch(n) --> starch(n+1)
