QUESTION 1

A mutation caused by exposure to gamma rays is called a spontaneous mutation

	a.	True
	b.	False
	c.	Sometimes, depending on the type of base change
	d.	Gamma rays do not cause mutations

QUESTION 2

A recessive mutation affecting an essential biochemical pathway can be detected________

	a.	when the organism is heterozygous for that mutation.
	b.	when the organism is homozygous for that mutation.
	c.	in either homozygous or heterozygous conditions.
	d.	only by sequencing (recessive mutations never show a phenotype).

QUESTION 3

During DNA replication, the newly synthesized chain grows by adding

	a.	nitrogenous bases
	b.	the sugar-phosphate backbone
	c.	nucleosides
	d.	dNTPs

QUESTION 4

During replication, the DNA strand 5â- AAGTCTAGCCTAG -3â will serve as a template for the polymerization of:

	a.	5â- CTAGGCTAGACTT -3â
	b.	5â - TTCAGATCGGATC -3â
	c.	5â - GATCCGATCTGAA -3â
	d.	3â - AAGTCTAGCCTAG -5â

QUESTIOn 5

Given the following DNA sequences, select which statement(s) is(are) correct.

Sequence 1:

5â-TGGACGCTAA-3â

3â-ACCTGCGATT-5â

Sequence 2:

5â-AATCGCAGGT-3â

3â-TTAGCGTCCA-5â

Sequence 3:

5â-ACCTGCGATT-3â

3â-TGGACGCTAA-5â

	a.	Sequences 1 and 2 are the same
	b.	Sequences 1 and 3 are the same
	c.	Sequences 2 and 3 are the same
	d.	Sequences 1, 2 and 3 are all different

QUESTION 6

Repetitive sequences in the genome are hotspots for:

	a.	Deamination
	b.	Depurination
	c.	Thymine dimer formation
	d.	Replication errors

QUESTION 7

Select which statement(s) about the Ames test is(are) correct

	a.	it has been designed to understand mutation repair systems in Salmonella typhimurium
	b.	it uses mammalian liver extract
	c.	it allows to study whether chemical compounds or their enzymatic breakdown products are mutagenic
	d.	it is based on whether a chemical compound causes reversion mutations from his+ to his-
	e.	two of the above are correct
	f.	three of the above are correct

QUESTION 8

Select which statement(s) is(are) correct.

	a.	All DNA strands have a direction, and it is specified by the carbons in the sugar backbone.
	b.	All DNA strands have a direction, and it is specified by hydrogen bonds between nucleotides.
	c.	In order to form proper base pairs in a double stranded DNA molecule, the two strands must run in opposite directions.
	d.	A and C are correct.
	e.	B and C are correct.

QUESTION 9

Studies of gene mutation frequencies have shown that:

	a.	mutations are rare, and genomes are generally stable.
	b.	mutation frequencies differ among organisms and also between genes, suggesting certain genes are more susceptible to mutation.
	c.	mutation frequencies are consistent between organisms, and each region of DNA is equally susceptible to random mutations.
	d.	Both A and B are correct.
	e.	Both A and C are correct.

QUESTION 10

The compound 5-bromodeoxyuridine (BrdU) is a derivative of uracil, and if BrdU becomes incorporated during DNA replication, it pairs with adenine. This compound is best classified as which type of mutagen?

	a.	base analog
	b.	base inducer
	c.	intercalating agent
	d.	oxidative agent
	e.	alkylating agent

QUESTION 11

The rate of mutation of the fruit fly is higher than the rate of mutation of Algae

True

False

QUESTION 12

Thymine dimers are most commonly caused by which of the following?

	a.	X-rays
	b.	Alkylating agents
	c.	U.V. irradiation
	d.	DNA intercalating agents

QUESTION 13

What chemical group is found in the 3â end of a DNA strand?

	a.	an alcohol
	b.	a hydroxyl
	c.	a methyl
	d.	a phosphate

QUESTION 14

What chemical group is found in the 5â end of a DNA strand?

	a.	an alcohol
	b.	a hydroxyl
	c.	a methyl
	d.	a phosphate

QUESTION 15

Which is the correct order of molecules binding to DNA during DNA replication?

	a.	Helicase, SSB, primase, DNA pol III, DNA pol I, ligase
	b.	SSB, DNA pol I, ligase, helicase, DNA pol I, primase
	c.	primase, helicase, DNA pol III, ligase, DNA pol I, SSB
	d.	SSB, helicase, primase, DNA pol III, DNA pol I, ligase

QUESTION 16

Which statement(s) is(are) correct about strand slippage?

	a.	It can cause disorders such as Huntingon disease.
	b.	It is a process that causes mutations altering the number of DNA repeats.
	c.	It is a process that incorporates nucleotide base analogs and trinucleotide repeats.
	d.	a and b are correct.
	e.	b and c are correct.
	f.	a, b and c are correct.

help needed asap.

chocolatesea-lion434

1. A colorblind woman marries a normal man. Which of thefollowing is true of their children?
a. all will be colorblind
b. all daughters will be normal and all sons will be carriers
c. all daughters will be colorblind and all sons will benormal
d. all daughters will be heterozygous and all sons will becolorblind
e. it is impossible to predict with any reasonable degree ofcertainty

2. Cleft chin is an autosomal dominant trait. A man with a cleftchin marries a woman with a round chin. What proportion of theirfemale progeny will show the trait?
a. 0%
b. 25%
c. 50%
d. 75%
e. 100%

3. Which of the following statements is false?
a. individuals with the same phenotype might have differentgenotypes
b. matings between individuals with dominant phenotypes cannotproduce offspring with recessive phenotypes
c. matings between individuals with recessive phenotypes usually donot produce offspring with dominant phenotypes
d. individuals with the same genotype might have differentphenotypes.
e. all the above are correct choices

4. True or False
a. DNA is composed of 4 different types of nucleotides T/F?
b. in the DNA of every species, the amount of adenine presentalways equals the amount of thymine, and the amount of cytosinealways equals the amount of guanine T/F?
c. in a nucleotide, the phosphate group is attached to thenitrogen-containing base, which is attached to the 5 carbon sugarT/F?
d. Watson and Crick built their model of DNA in the early 1950sT/F

5. MATCHING - each choice can be used more than once.
a. ribosomal RNA
b. DNA
c. mRNA
d. tRNA
e. RNA polymerase
-carries the genetic code sequence
-joins up with amino acids
-attaches the specific amino acids
-contains no uracil
-has anticodons
-determines amino acid sequence
-reads the codons
-contains codons
-has 2 polynucleotide chains
-has deoxyribose sugar
-makes RNA molecules in the nucleus

6. The number of base pairs in the human genome is about:
a. 1 million
b. 1 trillion
c. 10 billion
d. 75 billion

7. Pyrimidines are
a. single ringed
b. triple ringed
c. double ringed
d. none of these

8. Adenine is
a. double ringed
b. single ringed
c. a straight up chained carbon compound
d. a phospholipid

9._______ is the enzyme which puts together the correct DNA basesequence
a. DNA polymerase
b. RNA polymerase
c. helicase
d. adenine

fuchsiabeaver716

1. A colorblind woman marries a normal man. Which of thefollowing is true of their children?
a. all will be colorblind
b. all daughters will be normal and all sons will be carriers
c. all daughters will be colorblind and all sons will benormal
d. all daughters will be heterozygous and all sons will becolorblind
e. it is impossible to predict with any reasonable degree ofcertainty

2. Cleft chin is an autosomal dominant trait. A man with a cleftchin marries a woman with a round chin. What proportion of theirfemale progeny will show the trait?
a. 0%
b. 25%
c. 50%
d. 75%
e. 100%

3. Which of the following statements is false?
a. individuals with the same phenotype might have differentgenotypes
b. matings between individuals with dominant phenotypes cannotproduce offspring with recessive phenotypes
c. matings between individuals with recessive phenotypes usually donot produce offspring with dominant phenotypes
d. individuals with the same genotype might have differentphenotypes.
e. all the above are correct choices

4. True or False
a. DNA is composed of 4 different types of nucleotides T/F?
b. in the DNA of every species, the amount of adenine presentalways equals the amount of thymine, and the amount of cytosinealways equals the amount of guanine T/F?
c. in a nucleotide, the phosphate group is attached to thenitrogen-containing base, which is attached to the 5 carbon sugarT/F?
d. Watson and Crick built their model of DNA in the early 1950sT/F

5. MATCHING - each choice can be used more than once.
a. ribosomal RNA
b. DNA
c. mRNA
d. tRNA
e. RNA polymerase
-carries the genetic code sequence
-joins up with amino acids
-attaches the specific amino acids
-contains no uracil
-has anticodons
-determines amino acid sequence
-reads the codons
-contains codons
-has 2 polynucleotide chains
-has deoxyribose sugar
-makes RNA molecules in the nucleus

6. The number of base pairs in the human genome is about:
a. 1 million
b. 1 trillion
c. 10 billion
d. 75 billion

7. Pyrimidines are
a. single ringed
b. triple ringed
c. double ringed
d. none of these

8. Adenine is
a. double ringed
b. single ringed
c. a straight up chained carbon compound
d. a phospholipid

9._______ is the enzyme which puts together the correct DNA basesequence
a. DNA polymerase
b. RNA polymerase
c. helicase
d. adenine

brownherring865

BIOL308 Lecture 6: Lecture 6

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