ANP 1107 Lecture Notes - Lecture 11: Hematopoietic Stem Cell Transplantation, Infectious Mononucleosis, B Cell

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3. 1 list the 5 different types of leucocytes and give a brief description of the structure and function of each. 11,000 wbcs/ml inflammatory response within hrs: granulocytes & agranulocytes. > ***parasitic worms; cannot be phagocytized, but surround & release digestive enzymes. > modulate immune response allergies, asthma: (iii basophils: rarest wbcs (0. 5% of leukocytes); cytoplasmic granules contain histamine (vasodilator, makes blood vessels leaky & attracts other wbcs); s- or u-shaped dark purple nucleus. T lymphocytes (t cells): act directly against virus-infected cells, tumor cells. B lymphocytes (b cells): give rise to plasma cells that produce antibodies: (ii) monocytes: largest leukocytes; gray-blue cytoplasm + u- or kidney-shaped nucleus; in tissue, differentiate into macrophages. 3. 2 in flow chart form, summarize the main steps of leukopoeisis. Leukopoiesis is hormonally regulated according to body"s situation. Interleukins and colony-stimulating factors: hormones that regulate production of leukocytes, as needed.

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