ANP 1107 Study Guide - Midterm Guide: Immunocompetence, Mhc Class Ii, Defensin

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Protection against bacteria, viruses, parasites, toxins, tumor cells. Can leave bloodstream (diapedesis) to mount immune or inlammatory response. Amoeboid moion + chemotaxis (posiive chemotaxis is when they follow a trail to go where needed) Leukocytosis (count over 11,000 ) body"s response to bacterial or viral invasion, # can double within hours. Never let moneys eat bananas, in order of percent. Granulocytes more prominent staining granules, end in phil. Agranulocytes- not as dramaically granular, end in cyte. Spherical larger than rbc, lobed nuclei, wright"s stain is used. Basophils: rarest wbc"s, cytoplasmic granules contain histamine for inglammatory response (vasodilatory, makes blood vessels leaky and atract other wbc) Include lymphocytes, monocytes, no visible granules, nuclei spherical or kidney shaped. Monocytes: largest leukocytes, difereniate into macrophages when needed to clean up debris, phagocyic in chronic infecions (tb, also against viruses, some bacteria. Interleukins and colony simulaing factors: hormones that regulate producion of leukocytes as needed. 9 days (most die in line of duty)