HSS 1101 Lecture Notes - Lecture 5: Antibiotics, Aspirin, Prostaglandin
Document Summary
Response to drugs is inluenced by set and seing. Addicion: persistent dependence on substance or behaviour. Aspects of addicion include: excessive use of substance or behaviour, persistent desire to reduce or control use, incapacitaion due to use, withdrawal symptoms. The physiology of addicion: nt"s inluence receptor sites, tolerance: larger dose to get desired efects, withdrawal: drug causes an efect on the body. Signs of addicion: compulsion, loss of control, negaive consequences, denial. Receptor sites: specialized cells where drugs can atach themselves. Routes of administraion- the way the drug is taken into the body: oral ingesion: most common method, slow absorpion, injecion: rapid absorpion, inuncion: through the skin (patches) Synergism: 2+2=10: the efects of individual drugs are magniied beyond what is expected, most likely to happen when cns depressants combined. Antagonism: one drug blocks the acion of another @ a receptor site. Inhibiion: the efects of one drug are eliminated or reduced by another drug (antacids and aspirin)