HSS 3305 Lecture 5: Class 5 Inflammation and Repair
24 Feb 2016
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Document Summary
A nonspecific response to any agent that causes cell injury. Heat and redness: dilated blood vessels and slowing of blood through vessels. Swelling: accumulation of fluid and exudate due to extravasation of plasma. Tenderness and pain: irritation of nerve endings o response; actively phagocytic cell. Mononuclear cells (monocytes, macrophages) follow later to clean up tissue debris. Polymorphonuclear leukocyte cell: most important cell in acute inflammatory. Fluid mixture of protein, leukocytes, and tissue debris; proportion of protein and inflammatory cells vary. Fibrinous: rich in fibrinogen; coagulates and forms fibrin; produces a sticky film on surface of inflamed tissue. Adhesions: bands of fibrous tissue that bind adjacent tissue together. Hemorrhagic: inflammatory process ruptures many capillaries increasing red blood cells into the tissues. Fibrinous inflammation involving the surface of the heart (epicardium) and pericardium. The pericardial sac has been opened to expose the surface of the heart, which appears rough because fibrin has accumulated on the epicardium.
