HSS 4102 Lecture Notes - Lecture 20: Endocrine Disruptor, Lake Apopka, Estrogen Receptor
Document Summary
Hss4102 lecture 20 endocrine disruptors ii. Study: following survivors of hiroshima and nagasaki for more than 70 years. Video health effects of hiroshima and nagasaki atomic bombings (pws health hour) thyroid cancer and leukaemia first to strike solid cancers strike 20-30 years later children/young people and women are affected more severely. Video lake apopka: from fisherman"s paradise to pond of poison. Farming and fertilizer made the water green and full with algae. Possibly a good sing of regaining balance of the ecosystem. Chemical structures of estradiol (natural estrogen) and three of the endocrine disruptors discussed in this chapter. Bisphenol a: mechanism of the estrogen receptor within a general cell nucleus. Era and erbeta, err-ga a sxr (steroid and xenobiotic receptor. ) Des (diethylstilbestrol): the paradigmatic endocrine disruptor. aimed at obstetricians, 1956 advertisement promoted the use of des for maintaining at-risk pregnancies.