PHA 3112 Lecture Notes - Lecture 1: Drug Metabolism, Loading Dose, Adverse Drug Reaction
Document Summary
No two patients will respond identically to same drug regimen. Genetic factors alter drug metabolism unique drug reactions. Right drug, right patient, right dose, right route, right time, right documentation. Your responsibility does not end after the drug has been administered. A broad base of pharmacologic knowledge is needed to fully achieve the therapeutic objective. Checks and balances in drug administration check medications before they are given. Because the nurse actually administers drugs, they are the last person to. Nurses are the patient(cid:495)s last line of defense against medication errors. Knowledge of pharmokinetics helps choose most effective route, dosage and schedule that will: Achieve concentrations high enough to elicit desired response. Avoid concentrations that are too high and cause toxicity. Enteral: oral: epitherlial lining of gi tract and capillary wall, slow and variable absorption pattern, easy, convenient and inexpensive, required conscious patient, nausea and vomiting.