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PHA 3112 (35)

Class Notes for PHA 3112 at University of Ottawa

Clinical Pharmacology

Exam Study Guides for PHA 3112

Covers all exam topics.

PHA3112 Lecture 1: Peripheral Nervous System Notes

University of Ottawa PHA3112. Clinical Pharmacology Lecture 1 Basic Principles of Pharmacology Peripheral Nervous System Drugs 1 D. Burger, PhD Contents COURSE TEXTS............................................................

Pharmacology
PHA 3112
Pierre Fortier
PHA 3112 Lecture Notes - Lecture 1: Obstructive Sleep Apnea, Kussmaul Breathing, Tachypnea
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Respiratory Dysfunction Clinical Manifestations of Pulmonary Alterations 1. Pnea = respiration or breathing Dyspnea: difficult or uncomfortable breathing (shortness of breath, laboured, preoccupied w breathing) Orthopnea...

Pharmacology
PHA 3112
Pierre Fortier
PHA 3112 Lecture Notes - Lecture 3: Coronary Artery Disease, Atheroma, Coronary Circulation
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Cardiovascular Pathophysiology II Alterations in Cardiac Function Coronary Heart Disease (Coronaru Artery Disease) Two terms are interchangeable because: CHD is characterized by insufficient delivery of oxygenated blood to...

Pharmacology
PHA 3112
Pierre Fortier
PHA 3112 Lecture Notes - Lecture 4: Oncotic Pressure, Renal Blood Flow, Renal Artery
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Renal Pathophysiology The Filtration System Renal blood flow = 1200mlminute 25 cardiac output: 12 to the medulla; 90 cortex 99 (180L filtered24hrs) absorbed; 1 (11.8L of urine) excreted Constrictingdilating: limiting t...

Pharmacology
PHA 3112
Pierre Fortier
PHA 3112 Lecture Notes - Lecture 5: Respiratory Alkalosis, Respiratory Acidosis, Metabolic Alkalosis
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Fluid, Electrolytes AcidBase Pathophysiology Disorders of AcidBase Balance As [H ] increases pH decreases; blood = ~7.357.45 (slightly above neutral) pH < 7.35 = acidosis ; pH > 7.45 = alkalosis pH depends on: [HCO ] P...

Pharmacology
PHA 3112
Pierre Fortier
PHA 3112 Lecture Notes - Lecture 2: Disseminated Intravascular Coagulation, Intermittent Claudication, Venous Blood
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2. Cardiovascular 1 Alterations in Blood Flow Reduction in blood flow to tissues by arteries (=ischemia) o Any reduction in supply of O = h2poxia; due to: Anemia (reduction in hemoglobin) Impaired lung function (ex.: asth...

Pharmacology
PHA 3112
Pierre Fortier
PHA 3112 Lecture Notes - Lecture 7: Diabetes Mellitus Type 1, Diabetic Ketoacidosis, Diabetes Mellitus Type 2
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7. Diabetes Only treatment in early days: near starvation diet (return to case histories) Type 1 Diabetes insulindependent diabetes mellitus, IDDM) Need insulin replacement to live (no Cpeptide) Prevalence ~0.5 Incidenc...

Pharmacology
PHA 3112
Pierre Fortier
PHA 3112 Lecture Notes - Lecture 11: Megakaryoblast, Reticulocyte, Platelet
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11. Blood Disorders Intro to Blood Functions = transport, thermoregulation, defense Formed elements (blood cells) 45 of blood vol., RBC, WBC, platelets (thrombocytes) Hematocrit = of RBCs in blood volume Erythrocytes ...

Pharmacology
PHA 3112
Pierre Fortier
PHA 3112 Lecture Notes - Lecture 8: Pleomorphic Undifferentiated Sarcoma, Hepatocellular Carcinoma, Glioblastoma Multiforme
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Lecture 8 Neoplasia Cancer = proliferative disease (classified on basis of tissue from which it developed) Carcinomas: Common Adenocarcinomas (largest group) o Secretory Epithelia o Lung, colon, breast, pancreas, stomach,...

Pharmacology
PHA 3112
Pierre Fortier
PHA 3112 Lecture Notes - Lecture 10: Psychogenic Non-Epileptic Seizures, Status Epilepticus, Frontal Lobe
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Epilepsy other seizure disorders 200,000 people 4.4100,000; ~1 epilepsy by 20 Convulsion = intense paroxysm of involuntary repetitive muscular contractions Seizure = all paroxysm of involuntary repetitive muscular contrac...

Pharmacology
PHA 3112
Pierre Fortier
PHA 3112 Lecture Notes - Lecture 9: Jaw Jerk Reflex, Tuning Fork, Fasciculation
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Clinical Method of Neurology Approach to the Patient with Neurologic Illness Formulate a Diagnosis SS of history physical examination Anatomic diagnosis: localize disease (what part of brainns is affected) Syndromic di...

Pharmacology
PHA 3112
Pierre Fortier
PHA 3112 Lecture Notes - Lecture 6: Salivary Gland, Xerostomia, Small Intestine
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GI Disorders Introduction 1. Digestive Processes Ingestion: Process of taking food into the digestive tract Propulsion (directional): Mechanical: move food through the GI tract Swallowing: voluntary Peristalsis: involu...

Pharmacology
PHA 3112
Pierre Fortier
PHA 3112 Lecture Notes - Lecture 1: Drug Metabolism, Pharmacology, Institute For Operations Research And The Management Sciences

Introduction to Pharmacology Pharmacology: The study of drugs and their interactions with living systems study of the physical and chemical properties of drugs their biochemical properties of drugs their biochemical and ph...

Pharmacology
PHA 3112
frankfeiner
PHA 3112 Lecture Notes - Lecture 9: Cyclooxygenase, Colorectal Cancer, Cytochrome C Oxidase Subunit Ii

Lecture 9: COX Inhibitors, Joint disorders, Bone disorders Chapter 71. cyclooxygenase inhibitors: NSAIDS and acetaminophen (Drugs to know: acetaminophen, aspirin, celecoxib, ibuprofen ) MOA: inhibit COX (enzyme that conver...

Pharmacology
PHA 3112
frankfeiner
PHA 3112 Lecture Notes - Lecture 11: Peptic Ulcer, Aluminium Hydroxide, Aprepitant

LECTURE 11: Respiratory and GI disorders Drugs for Asthma albuterol beclomethasone cromolyn ipratropium salmeterol theophyline zafirlukast Drugs for Peptic Ulcer Disease aluminum hydroxide amoxicillin cimetidine omeprazole...

Pharmacology
PHA 3112
frankfeiner

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