PSY 3171 Lecture Notes - Lecture 12: Biology Of Depression, Twin, Mood Disorder
Document Summary
Relatives of people with mdd- no elevated risk for mania. Relatives of people with bd- elevated risk for mania and depression. Heritability"s of mdd and bo are related but distinct. Chart: (bottom, i am a twin and these are the disorders that i could get based on my twin, then looks at the type of twin and then the type of disorder) Bipolar disorder seems to make relatives prone to developing either disorder but the ones with major depressive disorder are only vulnerable to major depression disorder and the more shared biology you have the risks of getting it goes up. All mood disorders: concordance rate for identical twins is 2-3x higher than for fraternal twins. Mdd more likely if twin has mdd or bd (but at different concordance rates) Bd more likely only if twin also has bd (and especially for identical twins) Of identical twins concordant for a mood disorder, 80% are concordant for polarity