BIOA01H3 Lecture Notes - Lecture 28: Alpha Helix, Beta Sheet, Alternative Splicing
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Prokaryote vs eukaryote: (a) (rna polymerase) separate channels for 1. Vs (b) (primary transcript: transcription & translation @ separate compartments -> x combine or occur simultaneously complete transcription -> mrna move to another location -> start translation, 3 modifications: 1 - 5 cap @ 5 end (7-methylguanosine link to first rna nucleotide via 5 - to-5 phosphate linkage -> essential to translate mrna cuz x initiate translation w/x cap) Alternative splicing: pdc masking protein that binds to exon-intron junctions - > spliceosome x see junctions -> skip over -> exon in between introns removed as well -> control which exons can enter mrna (4 - transcript -> processing -> translation) Aa struc (lec 3 slide 13) alpha carbon + h & r & amino gp (nh2) & carboxyl gp (cooh) Aa - hydrophobic: ala, val, leu, ile, met, phe, trp, tyr.