BIOA01H3 Lecture Notes - Lecture 10: Translocon, Start Codon, Cytosol

18 views5 pages

pinkzebra766

14 Aug 2018

School

Department

Course

Professor

For unlimited access to Class Notes, a Class+ subscription is required.

3363410481 and 37710 others unlocked

BIOA01H3 Full Course Notes

Verified Note

18 documents

Document Summary

Ribosomes are a complex structure of rna and protein that bond with mrna. The large subunit includes three binding sites for trnas. These sites are called the a (aminoacyl), the. Initiation factors recruit the small ribosomal subunit and trnamet (first trna) and scan the mrna for an aug codon. binds to a(cid:374)d (cid:271)egi(cid:374) at the 5" (cid:272)ap. When the complex reaches an aug, the large ribosomal subunit joins, the initiation factors are released, and a trna complementary to the next codon binds to the a site. A reaction transfers the met to the amino acid on the trna in the a site, forming a peptide bond. Both the rna and protein components of the large subunit are required for peptide bond formation between amino acids. Carboxyl group of the methionine is attached to the amino group of the valine. Methionine is transferred from the peptide site to the trna in the aminoacyl site.

Related Questions

Facts about ribosomes

Indicate whether each of the following statements aboutribosomes is true or false.

1. Ribosomes are composed of tRNA and protein. TrueFalse
2. During translation in eukaryotes, some ribosomes remain free inthe cytoplasm while others attach to protein channels embedded inthe RER. TrueFalse
3. During initiation of translation, the small ribosomal subunitjoins to the mRNA and initiator rRNA, followed by the largeribosomal subunit. TrueFalse
4. When a ribosome first assembles on the mRNA, the initiator tRNAoccupies the A site while the P and E sites are empty.TrueFalse
5. During translation, a charged tRNA first binds to the ribosomeif its anticodon matches the codon in the E site. TrueFalse
6. A peptide bond forms between the amino acid attached to a tRNAin the A site and the growing polypeptide attached to a tRNA in theP site. TrueFalse
7. Uncharged tRNA molecules in the E site are ejected from theribosome. TrueFalse
8. No more than 2 tRNA molecules are bound to a ribosome at anygiven time. TrueFalse
9. During translocation of the ribosome, tRNA molecules move fromthe P site, to the A site, to the E site, and are then ejected fromthe ribosome. TrueFalse
10. During translation, an amino acid attached to a tRNA in the Asite is transferred to a growing polypeptide attached to a tRNA inthe P site. TrueFalse

periwinklemuskrat632

Facts about ribosomes

carmineraccoon103

Gene expression is a multi-step process. Place these events in the correct order.

Question 13 options:

charged tRNA molecules read the next codon, entering the A site of the ribosome.

Translocation of the mRNA to the cytoplasm.

Recruitment of RNA polymerase.

tRNA(Met) binds to the start codon AUG in the P site of the ribosome.

Assembly of small and large ribosome subunits on the mRNA.

Processing of the primary RNA molecule.

Release factors recognize the stop codon, signaling the release of the protein, mRNA and ribosome subunits.

Synthesis of primary RNA molecule, a direct copy of the DNA template.

Recognition of the mRNA by the small ribosome subunit .

Peptidyl transferase, transfers the amino acid of the incoming tRNA to the growing peptide chain.

Binding of transcription factors to the promoter.

blacklion206

BIOA01H3 Lecture Notes - Lecture 10: Translocon, Start Codon, Cytosol

BIOA01H3 Full Course Notes

Document Summary

Get access

Related Documents

BIOA01H3 Lecture Notes - Lecture 28: Nuclear Pore, Internal Ribosome Entry Site, Hydrolysis

BIOA01H3 Lecture Notes - Lecture 4: Aminoacyl Trna Synthetase, Start Codon, Transfer Rna

BIOA01H3 Lecture Notes - Lecture 31: Stop Codon, Eukaryotic Translation, Start Codon

Related Questions