BIOB11H3 Lecture Notes - Lecture 4: Tata Box, Spectrophotometry, Nucleolus
Document Summary
Lecture 4: introduction to transcription rrna synthesis & maturation. Pantothenic acid allowed the production of co-a: gave rise to the 1 gene 1 enzyme hypothesis. Generic biochemical pathway solution is add substance c: bypass metabolic block. Eukaryotic cells = transcription factors transcribe genes, shipped out of nucleus (mrna) and those associate with ribosomes to produce protein. We can link genes to behaviour/physiological traits. Dna template is read from 3" to 5" and synthesized from 5" to 3". Ntp = nucleotide triphosphate raw material for synthesis. Arrangement of elements in a bacterial promoter: blue lines = 2 strands of dna. Rna polymerase is inhibited if you consume amanita. Eukaryotic ribosome schematic: large subunit is built from 3 major rrnas, small subunit is built from 1 rrna, > 1 million ribosomes in a cell. Figure 11-11 - arrowhead shape = because of rrna organization one after another + actively transcribed by multiple rna polymerases.
