BIOC12H3 Lecture Notes - Lecture 3: Heterocyclic Compound, Cell Nucleus, Phosphodiester Bond

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Purines contain 9 atoms in their heterocyclic rings. Pyrimidines contain 6 atoms in the heterocyclic ring. On 2" c, in dna its h, and rna its oh. Primary structure of dna and rna is a single strand. Secondary structure: 2 complementary strand of dna bind together though base pairing in an antiparallel fashion. Rna can also have secondary structure, will look at that in a bit. Prokaryotic chromosomes can range in size from 0. 6 million base pairs to more than. Every base pair is separated by its neighbouring base pair by 0. 34 nm, 3. 4 angstrm. On dna: minor grove: when phosphodiester bonds are close together. Minor groove: when phosphodiester bonds are farther apart. Major groove is the site when protein binds to dna. Stacking of the dna bases in the interior of the helix provides stability to the molecule through the hydrophobic e ect and van der waals interactions.

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