Class Notes (834,037)
Canada (508,290)
BIOB10H3 (252)
Aarti Ashok (125)
Lecture 7

Notes for Lecture 7

7 Pages
Unlock Document

Biological Sciences
Aarti Ashok

MITOCHONDRIA: Structure & Function Mitochondria: origin -Mitochondria arose from aerobic prokaryotes - phagocytosed by eukaryotes -Mitochondria can divide within the cell - ^K]} Z}L]o]ZZ]}L_ Mitochondria: structure -Outer membrane (OMM) -Inner membrane (cristae) two are intermembrane space -Matrix GEL LIKE -2 membranes -2 aqueous compartments Mitochondria structure: OMM The outer mitochondrial membrane: -serves as the outer boundary of the organelle -has ~ 50% protein : 50% lipid ratio -has a diverse number of proteins that function as enzymes -several large protein channels J porins - Not specific & variety of moleciles -J-pleated sheets -can allow passage of large number of molecules ((e.g. ATP) -respond to conditions within the cell E.G. cell stress Mitochondria structure: IMM The inner mitochondrial membrane thin folds -has cristae -has ~75% protein: 25% lipid ratio -almost 100 different proteins present and has almost no cholesterol -is rich in a phospholipid called cardiolipin found in many bacterial membrane -very impermeable to molecules and has many channels & pumps highly selective Mitochondria structure: matrix -gel-like consistency from the high concentration of proteins and DNA -contains DNA (own genetic material) and ribosomes -mitochondrial DNA encodes ~ 37 genes in humans Mitochondrial proteins -The majority of proteins that function in the mitochondria are encoded by DNA in the cell nucleus -These proteins are translated on free ribosomes in the cytosol -They then need to be imported into the mitochondria POST-translational import protein
More Less

Related notes for BIOB10H3

Log In


Join OneClass

Access over 10 million pages of study
documents for 1.3 million courses.

Sign up

Join to view


By registering, I agree to the Terms and Privacy Policies
Already have an account?
Just a few more details

So we can recommend you notes for your school.

Reset Password

Please enter below the email address you registered with and we will send you a link to reset your password.

Add your courses

Get notes from the top students in your class.