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Lecture

Study Guide for Lecture 4: information from lecture slides + information added by prof during lecture

4 Pages
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Department
Environmental Science
Course Code
EESA10H3
Professor
Jovan Stefanovic

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EESA10 – Human Health and the Environment
LECTURE 4
Slide: Endocrine Disruptors
-Endocrine glands: organs in the body that produce
hormones (hormones regulate many different very
important processes in the body)
-Endocrine disruptors: chemicals that mimic hormones in
our bodies to interfere with the functions of hormone
glands. Endocrine disruptors also bind to hormone
receptors and alter gene functions
oIndirectly/consequent effects of the disruptors:
altered hormone production/transport/metabolism
-Fetuses are more sensitive/susceptible to endocrine
disruptors than adults
oThyroid hormone affects mental brain
development in fetuses
Slide: DES
-Synthetic estrogen used to prevent spontaneous abortion
(1948-1971)
oTaken by more than 1 million women from 1960
to 1970
-Daughters whose mothers took DES had increased
incidents of: reproductive organ dysfunction, abnormal
pregnancies, reduction in fertility, immune system
disorders
oAfter seeing the horrible results that the
daughters of those who took DES had to face, use
was discontinued
Slide: Endocrine Disruptors: Health Implications
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Description
EESA10 Human Health and the Environment LECTURE 4 Slide: Endocrine Disruptors - Endocrine glands: organs in the body that produce hormones (hormones regulate many different very important processes in the body) - Endocrine disruptors: chemicals that mimic hormones in our bodies to interfere with the functions of hormone glands. Endocrine disruptors also bind to hormone receptors and alter gene functions o Indirectlyconsequent effects of the disruptors: altered hormone productiontransportmetabolism - Fetuses are more sensitivesusceptible to endocrine disruptors than adults o Thyroid hormone affects mental brain development in fetuses Slide: DES - Synthetic estrogen used to prevent spontaneous abortion (1948-1971) o Taken by more than 1 million women from 1960 to 1970 - Daughters whose mothers took DES had increased incidents of: reproductive organ dysfunction, abnormal pregnancies, reduction in fertility, immune system disorders o After seeing the horrible results that the daughters of those who took DES had to face, use was discontinued Slide: Endocrine Disruptors: Health Implications www.notesolution.com
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