BIO120H1 Lecture Notes - Lecture 9: Transmembrane Protein, Protein Targeting, Glucose Transporter

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2 Feb 2013
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BIO120H1 Full Course Notes
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BIO120H1 Full Course Notes
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Just to recap, this slide is what we"ve been looking at in terms of vesicle transport. We looked at vesicle transport last lecture from the trans golgi network to the lysosome and how there"s a signal that is added on in the cis. Golgi onto proteins that are to be directed to the lysosome. These are for example, lysosomal hydrolases that need to end up in the lysosome and provide the functions of the lysosome in terms of degrading macromolecules. Just to recap, the trans golgi network is a major branching point for proteins that are to be sorted to different compartments in vesicles. Proteins that move through the golgi will end up in the trans golgi network and the vesicles that bud off the trans golgi network can have different destinations. We looked at the lysosome, going through either the late endosome or early endosome, these will eventually mature or become the lysosome.

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