BIO130H1 Lecture Notes - Lecture 5: Basal Lamina, Tight Junction, Adherens Junction
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BIO130H1 Full Course Notes
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Week 5 - interactions between cells and their environment. Epithelial: lined cavity, organs and surfaces, connective tissue underneath. In between them, there is the basement membrane/ basal lama: specialized extracellular matrix (can be considered as part of epithelial) Dermis: the connective tissue of the skin. Some of the cells are in contacts with the basal lamina. Nucleus: the hollow circle is the cytosol. Cells are attached to each other (some of them also attached to basal lamina) Different composition of ecm give tissues different properties. Integrin: transmembrane protein, help cell interact with ecm. Secreted by fibroblasts, epithelial and smooth muscle cells. Generally these cables are composed of three chains wound around each other in a triple helix. Gag: long, linear, chains of a repeating disaccharide. Highly negatively charged (attract na+ and water) One of the sugars is amino sugar (has n. A simple gag (not a proteoglycan, just gag)
