BIO230H1 Lecture Notes - Lecture 5: Nfat, Guanine, Amphiphile

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19 Nov 2016
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BIO230H1 Full Course Notes
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Lysosome (degradation of cellular parts no longer needed) Vacuole (animal cells have this too, but much more prominent in plants: storage of water, degradation- like animal lysosome. Cell wall (tough protective outer coat: keeps the shape of the cell whole organism. Lumen: aqueous parts inside organelles: within cell from different compartments, out of cell, into cell. Must be sorted to correct location to do work. Post-translational process: proteins are fully synthesized in cytosol before sorting. Unfolded: mitochondria, plastids: will fold once at target location. Endoplasmic reticulum (er) & proteins w/ er signal sequence: gated transport (both ways, transmembrane transport (one way, vesicular transport (most, but not all can go both directions) Small molecules diffuse through (< 5,000 daltons) Selective transport of macromolecules (rna, proteins, etc. ) Nuclear localization signal (nls: signal to go to nucleus. If specific protein not needed in high concentrations, then nir low, so less chance of protein w/ specific nls to get in]

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