BCH210H1 Lecture : Notes taken during tutorial

• School: UTSG
• Department: Biochemistry
• Course: BCH210H1
• Professor: Dave Tulumello

Document Summary

B is likely to be inner leaflet because it is enriched in a negatively charged lipid phosphotidylserine. Inside of cell is generally negatively charged (*****: inner leaflet negatively charged, calsium concentration high towards inner leaflet calcium. Membrane proteins cannot diffuse in the plane of the membrane they can: can diffuse along with the lipids, lipids cannot flip between leaflets same with membrane proteins. Sugar molecules attached to proteins o linked attached via oxygen serine and threonine. Membranes aren t just lipids sugars also important. N linked via asparagine amine for linkage attached to amino acid. Important for cell recognition: rbc has many complex type of sugar linkages, acidic groups at end of them allow. Single-span type one and two: has to do what part of chain is inside cell, outside cell. If n terminal inside cell type two membrane protein. Multi spanning 2 to 24: 7 span common in receptors.