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BCH210H1 (352)
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Department
Biochemistry
Course
BCH210H1
Professor
Dave Tulumello
Semester
Fall

Description
TutorialOctober 21 2011QUESTIONSHypothetical phospholipid composition of RBC inner and outer leaflets B is likely to be inner leaflet because it is enriched in a negatively charged lipidphosphotidylserineo Inside of cell is generally negatively chargedo inner leaflet negatively charged o Calsium concentration high towards inner leafletcalciumMembrane proteins cannot diffuse in the plane of the membranethey can o Can diffuse along with the lipids o Lipids cannot flip between leafletssame with membrane proteins From lecturesMembranes arent just lipidssugars also important Sugar molecules attached to proteinsO linked attached via Oxygenserine and threonine N linked via asparagineamine for linkage attached to amino acid Both N acetyl amineComplex chains allow for functions in cell Different modifications at each step Important for cell recognitiono RBC has many complex type of sugar linkages acidic groups at end of themallow RBC to not interact with each othern
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