BIO130H1 Lecture Notes - Eukaryotic Transcription, Cistron, Genetic Recombination
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BIO130H1 Full Course Notes
Verified Note
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Document Summary
Dots at the end - initial ribosome assembly. Cells can change their transcription (needs more of a certain thing) Base and sugar differences between rna and dna. Rna nucleotides linked by phosphodiester bonds through ribose-po4. The building blocks of life page 9 ssdna. Sigma factor binds to core rna polymerase - holoenzyme or rna polymerase holoenzyme. Holoenzyme binds weakly and when it encounters the promoter, the sigma factor recognizes the promoter and binds really tightly (no atp) Bacteria, many sigma factors and many different kinds, each recognizing a different set of genes. Transcription does not start where the promoter region is but further on sigma factor released termination structure. Rna elongation termination made slowly; doesn"t need primer (10 ribonucleotides long); start, something doesn"t work, start again. Highly processive (how fast it reads and adds nucleotides; starts out slow and goes faster in elongation mode)
