HMB265H1 Lecture 14: Genetic Mapping & complex Traits (Lecture 14)

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23 Mar 2016
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HMB265H1 Full Course Notes
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Mapping of the qtl is a way to try to locate where these loci are in the gene. On the graph genotype at this locus and phenotype of the fruit size co-segregate. Qtl is 100 times more likely than the probability of your data given no qtl. Probability of linkage probability that given data says you have a qtl nearby having a marker that is linked. Dissecting the basis of tomato fruit size: qtl controlling tomato fruit size were mapped went across and looked at all the lod scores. Able to isolate part of the chromosome that looked like it was a qtl (based on lod score) Qtl was found to be located at a certain region (interval) on the chromosome mapped the. Qtl to this interval: create recombinant inbred lines (rils) Generated by inbreeding selected individuals down a lineage create inbred lines out of f2 generation.

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